Protein Details: Aquaporin-3

Protein ID

ICDB_Pro_0157

Protein Name

Aquaporin-3

Gene Name

AQP3

Organism

Laccaria bicolor (Bicoloured deceiver) (Laccaria laccata var. bicolor)

Length

330 amino acids

AlphaFoldDB

AF-I1Z8E6-F1-model_v4.pdb

Function

Water channel required to facilitate the transport of water across membranes. Mediates also the transport of carbon dioxide across the membrane.

Sequence

MSATPIIHLRDVKKRTGVLNAWERVRNKPQVHWAMECFAEALGVFFYVYFGLGSTAAWVIGNILKQSGLSSVFQIGFAYAFGILFAIGVCAATSGGHFNPCVTIAFTIFRGFPPLKAVRYIVAQILGAYIASALVYNQWKVLIVESELLLKQAGVYETTMFTPNGPAGIFALYLLPGAQTLPRAFLNEFVNCFVLALVIWAALDPTSFMIPPVMAPFIIAAAYAGSIWGYAVPAISLNSARDIGCRLFALTIWGKSAAGGSYSAIAALVNIPATLLAAVVYELFLVDSDRVVAGSHLEFMNVAANHRRHRQQAEDDNLVEADDSSQEKPV

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Location

DOI ID

10.1111/nph.13098; 10.1111/pce.12552; 10.1007/s00572-015-0643-6